Investigation of the Intrinsic Spatial Resolution of an Intensified EMCCD Scintillation Camera.
Investigation of the Intrinsic Spatial Resolution of an Intensified EMCCD Scintillation Camera.
复制标题
增强型 EMCCD 闪烁相机固有空间分辨率的研究。
DOI：
10.1109/tns.2008.2004278
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发表时间：
2008
影响因子：
1.8
通讯作者：
Fu,G
中科院分区：
文献类型：
--
作者：
Meng,LJ;Fu,G
在本文中，我们提出了一个实验和Monte Carlo调查的内在空间分辨率，可以实现与增强型电子倍增电荷耦合器件（I-EMCCD）伽马相机。该探测器具有极低的读出噪声、超高的空间分辨率和直径约80 mm的大有效区域，非常适合小动物成像应用。比较了在不同的实验条件下，采用不同的色散补偿器获得的本征探测器分辨率。在这项研究中，简单的质心方法进行了比较，两个模型拟合方法寻找伽马射线相互作用的位置。Monte Carlo模拟结果表明，采用合适的探测器结构，对于27-35 keV的γ射线，本征分辨可达~ 30 μ m半高宽。I-EMCCD闪烁相机为未来超高分辨率SPECT成像应用提供了一个有前途的候选者。
In this paper, we present an experimental and Monte Carlo investigation of the intrinsic spatial resolution that can be achieved with the intensified electron-multiplying charge-coupled device (I-EMCCD) gamma camera . This detector has a very low readout noise, an ultra-high spatial resolution and a large active area of ~ 80 mm diameter, which is well-suited for small animal imaging applications. The intrinsic detector resolutions achieved with different scintillators and under different experimental conditions were compared. In this study, the simple centroiding method was compared with two model-fitting approaches for finding the locations of gamma ray interactions. The results from Monte Carlo simulation have demonstrated that with an appropriate detector configuration, it is possible to achieve an intrinsic resolution of ~ 30 mum FWHM for detecting 27-35 keV gamma rays. The I-EMCCD scintillation camera offers a promising candidate for future ultra-high resolution SPECT imaging applications.