A DISTRIBUTED MODEL OF EXCHANGE PROCESSES WITHIN THE OSTEON
A DISTRIBUTED MODEL OF EXCHANGE PROCESSES WITHIN THE OSTEON
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DOI：
10.1016/0021-9290(92)90263-z
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发表时间：
1992-04-01
影响因子：
2.4
通讯作者：
YANG, L
中科院分区：
文献类型：
--
作者：
MCCARTHY, ID;YANG, L
为了理解骨单位内的各种交换过程，已经开发了一个数学模型来描述该系统，该模型允许轴向和径向方向上的浓度梯度以及细胞消耗和结合到骨表面。讨论了模型参数的正常值，并研究了模型参数对模型行为的影响。该模型支持这样的观点，即在血液和骨细胞之间的运输中，仅扩散可能是低效的机制。
In order to understand various exchange processes within the osteon, a mathematical model to describe the system has been developed which allows for concentration gradients in the axial and radial directions as well as cellular consumption and binding to bone surface. The normal values for the model parameter are discussed and the effects of the model parameters on the behaviour of the model are investigated. This model supports the idea that diffusion alone may be an inefficient mechanism in transport between blood and osteocytes.