Cytokine concentrations in sputum of asthmatic patients
Cytokine concentrations in sputum of asthmatic patients
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DOI：
10.1159/000237234
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发表时间：
1996-01-01
影响因子：
2.8
通讯作者：
Adachi, M
中科院分区：
文献类型：
--
作者：
Konno, S;Gonokami, Y;Adachi, M
To examine whether levels of inflammatory cytokines and eosinophil cationic protein (ECP) in the sputum reflect the severity of bronchial asthma, we measured their levels in the sputum of symptomatic and asymptomatic asthmatics. Interleukin (IL)-1 beta, IL-5, IL-6, IL-8, RANTES, tumor necrosis factor-alpha and ECP concentrations in the sputum of symptomatic patients were significantly higher than in asymptomatic subjects. These findings suggest that these inflammatory cytokines are involved in the exacerbation of asthma.
