Visual Working Memory Enhances the Neural Response to Matching Visual Input
Visual Working Memory Enhances the Neural Response to Matching Visual Input
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DOI：
10.1523/jneurosci.3418-16.2017
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发表时间：
2017-07-12
影响因子：
5.3
通讯作者：
Sterzer, Philipp
中科院分区：
文献类型：
--
作者：
Gayet, Surya;Guggenmos, Matthias;Sterzer, Philipp
视觉工作记忆（VWM）用于为后续的目标导向行为维持可用的视觉信息。vwm的内容已被证明会影响对并发视觉输入的行为反应，这表明来自vwm和来自感觉输入的视觉表征利用了共享的神经基质（即vwm存储的感觉招募立场）。在这里，我们假设，视觉信息维持在视觉记忆中会增强神经对与视觉记忆内容相匹配的并发视觉输入的反应。为了验证这一假设，我们测量了15名人类参与者（3名男性）对任务无关刺激的fMRI BOLD反应，他们同时执行延迟匹配样本任务。在这个任务中，观察者被顺序地呈现两个形状刺激和一个回溯提示，指示这两个形状中的哪一个应该被记忆以供随后的识别。在保持间隔期间，外围视野中会短暂出现一个与任务无关的形状（探针），该形状可能与记忆刺激的形状类别匹配或不匹配。我们发现，尽管有相同的视觉刺激，当探针刺激与同时记忆的内容匹配而不是不匹配时，探针刺激引发了更强的bold反应，并允许增加形状分类性能。我们的研究结果表明，视频以一种特定于内容的方式增强了对并发视觉输入的神经反应。这一发现与参与感觉处理的神经群被招募用于视觉图像存储的观点是一致的，它为大量的行为研究提供了一个共同的解释，在这些研究中，视觉图像匹配的视觉输入引发了更强的行为和感知反应。
Visual working memory (VWM) is used to maintain visual information available for subsequent goal-directed behavior. The content ofVWM has been shown to affect the behavioral response to concurrent visual input, suggesting that visual representations originating fromVWMand from sensory input draw upon a shared neural substrate (i. e., a sensory recruitment stance onVWMstorage). Here, we hypothesized that visual information maintained inVWMwould enhance the neural response to concurrent visual input that matches the content ofVWM. To test this hypothesis, we measured fMRI BOLD responses to task-irrelevant stimuli acquired from 15 human participants (three males) performing a concurrent delayed match-to-sample task. In this task, observers were sequentially presented with two shape stimuli and a retro-cue indicating which of the two shapes should be memorized for subsequent recognition. During the retention interval, a task-irrelevant shape (the probe) was briefly presented in the peripheral visual field, which could either match or mismatch the shape category of the memorized stimulus. Weshow that this probe stimulus elicited a strongerBOLDresponse, and allowed for increased shape-classification performance, whenit matched rather than mismatched the concurrently memorized content, despite identical visual stimulation. Our results demonstrate thatVWMenhances the neural response to concurrent visual input in a content-specific way. This finding is consistent with the view that neural populations involved in sensory processing are recruited forVWMstorage, and it provides a common explanation for a plethora of behavioral studies in whichVWMmatching visual input elicits a stronger behavioral and perceptual response.