Behavioral, perceptual, and neural alterations in sensory and multisensory function in autism spectrum disorder.
Behavioral, perceptual, and neural alterations in sensory and multisensory function in autism spectrum disorder.
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DOI：
10.1016/j.pneurobio.2015.09.007
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发表时间：
2015-11
影响因子：
6.7
通讯作者：
Wallace MT
中科院分区：
文献类型：
--
作者：
Baum SH;Stevenson RA;Wallace MT
虽然自自闭症的第一个临床描述以来，感觉处理的挑战已经被注意到，但直到2013年第五版精神疾病诊断和统计手册（DSM-5）发布，感觉问题才被列为自闭症谱系障碍（ASD）诊断特征的核心症状的一部分。由于感觉信息形成了高阶社会和认知功能的基石，我们认为感觉处理不仅是拼图的另一块，而且是表征和理解ASD的关键基石。在这篇综述中，我们讨论了目前已知的ASD感觉处理，感觉功能如何适合当代模型的ASD，以及了解什么是在个体与非ASD之间观察到的感觉和社会沟通的潜在神经处理的差异。除了强调与ASD相关的感觉功能，我们还强调了多感觉处理在建立感知和认知表征中的重要性，以及多感觉整合的缺陷也可能是ASD的核心特征。
Although sensory processing challenges have been noted since the first clinical descriptions of autism, it has taken until the release of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) in 2013 for sensory problems to be included as part of the core symptoms of autism spectrum disorder (ASD) in the diagnostic profile. Because sensory information forms the building blocks for higher-order social and cognitive functions, we argue that sensory processing is not only an additional piece of the puzzle, but rather a critical cornerstone for characterizing and understanding ASD. In this review we discuss what is currently known about sensory processing in ASD, how sensory function fits within contemporary models of ASD, and what is understood about the differences in the underlying neural processing of sensory and social communication observed between individuals with and without ASD. In addition to highlighting the sensory features associated with ASD, we also emphasize the importance of multisensory processing in building perceptual and cognitive representations, and how deficits in multisensory integration may also be a core characteristic of ASD.