Rotavirus infection and histo-blood group antigens in the children hospitalized with diarrhoea in China

Rotavirus infection and histo-blood group antigens in the children hospitalized with diarrhoea in China
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我国腹泻住院儿童轮状病毒感染及组织血型抗原分析

DOI:
10.1016/j.cmi.2016.06.007
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发表时间:
2016-08-01
影响因子:
14.2
通讯作者:
Duan, Z. -J.
Duan, Z. -J.
中科院分区:
医学1区
文献类型:
--
作者:
Sun, X.;Guo, N.;Duan, Z. -J.

文献摘要

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为了探讨轮状病毒(RV)感染与组织血型抗原(HBGA)之间的关系,对2014年11月至2015年2月在中国住院的腹泻儿童进行了一项横断面研究。总共收集了424份粪便、唾液和口腔细胞样本。对于 125 个 RV 阴性样本,92% (104/125) 为分泌者/部分分泌者,8% (10/125) 为非分泌者。在299个RV阳性样本中,277个为P[8],22个为P[4]。除一名非分泌者 P[8] (0.3%, 1/299) 外,所有 P[4] 和 P[8] 阳性个体均为分泌者/部分分泌者。这些发现表明 P[8] 和 P[4] RV 优先感染分泌者/部分分泌者 (p < 0.001)。 X. Sun,(C) 2016 年欧洲临床微生物学和传染病学会。由爱思唯尔有限公司出版。保留所有权利。
To explore the association between rotavirus (RV) infection and histo-blood group antigens (HBGAs), a cross-sectional study was conducted in children hospitalized with diarrhoea in China from November 2014 to February 2015. In total, 424 sets of stool, saliva and buccal cell samples were collected. For the 125 RV-negative samples, 92% (104/125) were secretors/partial secretors, 8% (10/125) were non-secretors. Among the 299 RV-positive samples, 277 were P[8] and 22 were P[4]. All P[4] and P[8] positive individuals were secretors/partial secretors except for one P[8] (0.3%, 1/299), which was a non-secretor. These findings indicate that P[8] and P[4] RVs preferably infect secretors/partial secretors (p < 0.001). X. Sun, (C) 2016 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.