Interpolymer Association of Cholesterol Pendants Linked to a Polyelectrolyte As Studied by Quasielastic Light Scattering and Fluorescence Techniques
Interpolymer Association of Cholesterol Pendants Linked to a Polyelectrolyte As Studied by Quasielastic Light Scattering and Fluorescence Techniques
复制标题
通过准弹性光散射和荧光技术研究了与聚电解质连接的胆固醇侧链的互聚物缔合
作者：
S. Yusa;and Akihito Hashidzume;Y. Morishima
通过准弹性光散射和荧光技术研究了2-(丙烯酰胺基)-2-甲基丙磺酸钠(AMPS)和胆固醇6-甲基丙烯酰氧基己酸酯(Chol-C5-MA)的无规共聚物在0.1 M NaCl水溶液中的缔合行为，以进一步了解我们之前提出的“分子间桥接的花型胶束”的结构和性质。当共聚物中 Chol-C5-MA 含量低至 1 mol% 时，发现单聚体与互聚物聚集体共存，与聚合物浓度 (CP) 无关，范围为 0.1 < CP < 10 g/L。然而，当 Chol-C5-MA 含量增加到 5 mol% 时，几乎所有聚合物链都形成了多元聚合物聚集体，可以将其视为花型胶束的组装体，其中聚合物链通过 Chol 缔合进行“交联”。通过时间分辨荧光淬灭，5 mol% Chol-C5-MA 的共聚物中 Chol 部分的聚集数估计为 17−19。
The association behavior of random copolymers of sodium 2-(acrylamido)-2-methylpropanesulfonate (AMPS) and cholesteryl 6-methacryloyloxyhexanoate (Chol-C5-MA) in 0.1 M NaCl aqueous solutions was investigated by quasielastic light scattering and fluorescence techniques to gain further insights into the structures and properties of their “intermolecularly bridged flower-type micelles” which we had proposed previously. When the Chol-C5-MA content in the copolymer was as low as 1 mol %, unimers were found to coexist with the interpolymer aggregates independent of the polymer concentration (CP) in a range 0.1 < CP < 10 g/L. However, when the Chol-C5-MA content was increased to 5 mol %, virtually all the polymer chains form multipolymer aggregates which can be viewed as an assembly of flower-type micelles where polymer chains are “cross-linked” via Chol associations. The aggregation number of Chol moieties was estimated to be 17−19 for the copolymer of 5 mol % Chol-C5-MA by a time-resolved fluorescence quenchin...