A Dielectric Rod Antenna for Picosecond Pulse Stimulation of Neurological Tissue.
A Dielectric Rod Antenna for Picosecond Pulse Stimulation of Neurological Tissue.
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DOI：
10.1109/tps.2016.2537213
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发表时间：
2016-04
期刊：
影响因子：
--
通讯作者：
Xiao S
中科院分区：
文献类型：
--
作者：
Petrella RA;Schoenbach KH;Xiao S
本文研究了一种介质加载宽带杆形天线作为皮下组织脉冲传输系统。应用100 ps电脉冲的模拟结果表明，它允许我们产生临界电场的生物效应，如脑刺激，在几厘米的范围内。为了达到生物效应的临界电场，在2cm的深度处约为20 kV/cm，输入电压需要为175 kV。在该位置处的大脑中的电场斑点大小约为1cm 2。实验研究在自由空间中的锥形天线（天线系统的一部分）与氮化铝作为电介质证实了模拟的准确性。这些结果为完整天线系统的高电压原位实验和向生物组织输送脉冲奠定了基础。
A dielectrically loaded wideband rod antenna has been studied as a pulse delivery system to subcutaneous tissues. Simulation results applying 100 ps electrical pulse show that it allows us to generate critical electric field for biological effects, such as brain stimulation, in the range of several centimeters. In order to reach the critical electric field for biological effects, which is approximately 20 kV/cm, at a depth of 2 cm, the input voltage needs to be 175 kV. The electric field spot size in the brain at this position is approximately 1 cm2. Experimental studies in free space with a conical antenna (part of the antenna system) with aluminum nitride as the dielectric have confirmed the accuracy of the simulation. These results set the foundation for high voltage in situ experiments on the complete antenna system and the delivery of pulses to biological tissue.