Vaccine preventable diseases in returned international travelers Results from the GeoSentinel Surveillance Network
Vaccine preventable diseases in returned international travelers Results from the GeoSentinel Surveillance Network
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DOI：
10.1016/j.vaccine.2010.09.009
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发表时间：
2010-10-28
期刊：
影响因子：
5.5
通讯作者：
Wilson, Mary E.
中科院分区：
文献类型：
--
作者：
Boggild, Andrea K.;Castelli, Francesco;Wilson, Mary E.
疫苗可预防疾病（VPDs）是威胁国际旅行者的疾病，但其流行病学特征尚不清楚。我们分析了GeoSentinel监测网络数据库中37542名患病回国旅行者的记录。与伤寒相关的因素包括VFR旅行（p <0016）中南亚（p <0.001）商务旅行与流行性感冒有关（p <0.001）和较长时间的甲型肝炎病毒旅行（p = 0.02）29%的VPD患者进行了旅行前咨询。至少55%的VPD患者作为住院患者接受治疗，而非VPD患者为9.5%。VPD肺炎球菌脑膜炎伤寒和狂犬病各导致1例死亡VPD是旅行者发病率和潜在死亡率的重要因素高住院率使其成为旅行前干预的有吸引力的目标（C）2010 Elsevier Ltd版权所有
Vaccine preventable diseases (VPDs) threaten international travelers but little is known about their epidemiology in this group We analyzed records of 37 542 ill returned travelers entered into the GeoSentinel Surveillance Network database Among 580 (1 5%) with VPDs common diagnoses included enteric fever (n = 276) acute viral hepatitis (n = 148) and influenza (n = 70) Factors associated with S typhi Included VFR travel (p < 0 016) to South Central Asia (p < 0 001) Business travel was associated with influenza (p < 0 001) and longer travel with hepatitis A virus (p = 0 02) 29% of those with VPDs had pre-travel consultations At least 55% of those with VPDs were managed as inpatients compared to 9 5% of those with non-VPDs Three deaths occurred one each due to pneumococcal meningitis S typhi and rabies VPDs are significant contributors to morbidity and potential mortality in travelers High rates of hospitalization make them an attractive target for pre-travel intervention (C) 2010 Elsevier Ltd All rights reserved