Acute exposure to a 50 Hz magnetic field impairs consolidation of spatial memory in rats
Acute exposure to a 50 Hz magnetic field impairs consolidation of spatial memory in rats
复制标题
DOI：
10.1016/j.nlm.2007.07.010
复制
发表时间：
2007-11-01
影响因子：
2.7
通讯作者：
Taherian, Abbas Ali
中科院分区：
文献类型：
--
作者：
Jadidi, Majid;Firoozabadi, Seyed Mohammad;Taherian, Abbas Ali
这项研究计划用水迷宫评估暴露在磁场中对巩固和恢复海马区依赖的空间记忆的影响。在实验1和实验2中，大鼠被训练在一个隐藏版本的(空间)水迷宫任务中，包括四个实验中的两个区块。48h后检测大鼠空间记忆保持情况。训练后立即暴露在50赫兹8mT的磁场中20分钟，而不是2mT的磁场会损害保持能力。同一时间，在保持性测试之前不久暴露在同一时间没有任何效果。在实验3中，大鼠被训练在有提示版本的水迷宫中，实验分为两组，每组四次。训练结束后立即暴露在8mT的磁场中20min不会损害保持能力。这些发现表明，短时间暴露在8mT的50赫兹磁场中会损害空间记忆的巩固。(C)2007 Elsevier Inc.保留所有权利。
This study was planned to evaluate the effect of an exposure to magnetic fields on consolidation and retrieval of hippocampus dependent spatial memory using a water maze. In Experiments 1 and 2, rats were trained in a hidden version (spatial) of water maze task with two blocks of four trials. The retention of spatial memory was evaluated 48 h later. Exposure to a 50 Hz 8 mT, but not 2 mT magnetic fields for 20 min immediately after training impaired retention performance. The same time exposure shortly before retention testing had no effect. In Experiment 3, rats were trained in a cued version of water maze with two blocks of four trials. Exposure to magnetic field at 8 mT for 20 min immediately after training did not impair retention performance. These findings indicate that acute exposure to a 50 Hz magnetic field at 8 mT for short time can impair consolidation of spatial memory. (C) 2007 Elsevier Inc. All rights reserved.