Pyridine-catalyzed desulfonative borylation of benzyl sulfones
Pyridine-catalyzed desulfonative borylation of benzyl sulfones
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DOI：
10.1039/c9ob01099h
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发表时间：
2019-08-21
影响因子：
3.2
通讯作者：
Crudden, Cathleen M.
中科院分区：
文献类型：
--
作者：
Maekawa, Yuuki;Ariki, Zachary T.;Crudden, Cathleen M.
本文报道了无过渡金属、吡啶催化的苄基砜与二硼频哪醇酯（B（2）pin（2））的双磺化硼化反应。各种二苯甲基和苄基硼酸酯可以从容易制备的砜衍生物合成。环砜的硼基化伴随开环也进行以提供相应的磺酸盐，其可以转化为官能化砜和磺酰胺。
Herein, we report the transition-metal free, pyridine-catalyzed desulfonative borylation of benzyl sulfones with bis(pinacolato)diboron (B(2)pin(2)). A variety of benzhydryl- and benzyl boronic esters could be synthesized from readily prepared sulfone derivatives. The borylation of cyclic sulfones accompanied by ring opening also proceeded to afford the corresponding sulfonate, which could be converted into functionalized sulfones and sulfonamides.