Prevalence of clinical mitral-valve prolapse in 1169 young women.
Prevalence of clinical mitral-valve prolapse in 1169 young women.
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1169 名年轻女性临床二尖瓣脱垂的患病率。
DOI：
10.1056/nejm197605132942004
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发表时间：
1976
期刊：
影响因子：
--
通讯作者：
A. Bryson
中科院分区：
文献类型：
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作者：
P. Procacci;S. Savran;S. Schreiter;A. Bryson
1169名年轻女性前瞻性检查二尖瓣脱垂的存在，表现为收缩期中期非射血咔嗒声或收缩期晚期杂音（或两者兼而有之）。在1169名女性中，74名（6.3%）有二尖瓣脱垂的生理表现。74例患者中有68例（92%）有收缩期中期非射血性咔嗒声，57例咔嗒声伴有收缩期晚期杂音。6例（8%）患者仅听到收缩期晚期杂音。临床诊断为二尖瓣脱垂的74例患者超声心动图显示脱垂的60例（81%）。14例（19%）超声心动图阴性。我们得出结论，二尖瓣脱垂在临床上约6.3%的健康年轻女性中存在。
Eleven hundred and sixty-nine young women were prospectively examined for the presence of mitral-valve prolapse as manifested by midsystolic non-ejection click or late systolic murmur (or both). Of the 1169 women 74 (6.3%) had physical findings consistent with mitral-valve prolapse. Sixty-eight of the 74 (92%) had midsystolic non-ejection click, and in 57 the click was accompanied by a late systolic murmur. In six (8%) only a late systolic murmur was heard. Echocardiography on all patients with clinical diagnosis of mitral-valve prolapse showed patterns of prolapse in 60 of 74 (81%). Fourteen (19%) had negative echocardiograms. We conclude that mitral-valve prolapse is clinically present in approximately 6.3% of otherwise healthy young women.