Contributions of magnetic source imaging to the understanding of dyslexia.
Contributions of magnetic source imaging to the understanding of dyslexia.
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DOI：
10.1053/spen.2002.35506
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发表时间：
2002-09
影响因子：
2.7
通讯作者：
Shirin Sarkari;P. Simos;J. Fletcher;E. Castillo;J. Breier;A. Papanicolaou
中科院分区：
文献类型：
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作者：
Shirin Sarkari;P. Simos;J. Fletcher;E. Castillo;J. Breier;A. Papanicolaou
诵读困难症的问题是难以学习印刷文字如何映射到口语。在三项研究中使用了磁源成像协议。第一项对有阅读障碍的儿童的研究显示，右颞顶区域的活动更大。第二项研究表明，在阅读习得的最初阶段，存在着异常的神经回路。第三项研究表明，在强化教学后，异常的轮廓可以正常化。这些发现表明，诵读困难代表了神经回路中的功能缺陷，该神经回路介导了印刷品到声音的转换，这在适当的指导下是可以改变的。
The problem in dyslexia is difficulty learning how the printed word maps onto spoken language. Magnetic Source Imaging protocols were used in three studies. The first study with dyslexic children showed greater activity in the right temporoparietal region. The second study showed the aberrant neural circuit was present in initial stages of reading acquisition. The third study demonstrated that the aberrant profile could be normalized following intensive instruction. These findings suggest that dyslexia represents a functional deficit in the neural circuit that mediates the conversion of print to sound, which is amenable to change given adequate instruction.