Absence of detectable replication of human bocavirus species 2 in respiratory tract.

Absence of detectable replication of human bocavirus species 2 in respiratory tract.
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DOI:
10.3201/eid1509.090394
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发表时间:
2009-09
影响因子:
11.8
通讯作者:
Simmonds P
Simmonds P
中科院分区:
医学2区
文献类型:
--
作者:
Chieochansin T;Kapoor A;Delwart E;Poovorawan Y;Simmonds P

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人博卡病毒(HBoV)通常感染幼儿,并与呼吸道疾病有关;不同HBoV-2种的疾病相关性尚不清楚。在粪便样本中频繁检测到HBoV-2表明其在英国和泰国广泛传播,但在6524份呼吸道样本中未检测到HBoV-2表明其在嗜性/发病机制上可能与HBoV-1不同。
Human bocavirus (HBoV) commonly infects young children and is associated with respiratory disease; disease associations of the divergent HBoV-2 species are unknown. Frequent HBoV-2 detection in fecal samples indicated widespread circulation in the United Kingdom and Thailand, but its lack of detection among 6,524 respiratory samples indicates likely differences from HBoV-1 in tropism/pathogenesis.