Linkage studies on glyoxalase I (GLO), pepsinogen (PG), spinocerebellar ataxia (SCA1), and HLA.
Linkage studies on glyoxalase I (GLO), pepsinogen (PG), spinocerebellar ataxia (SCA1), and HLA.
复制标题
乙二醛酶 I (GLO)、胃蛋白酶原 (PG)、脊髓小脑共济失调 (SCA1) 和 HLA 的关联研究。
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
P. Terasaki
中科院分区：
文献类型：
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作者：
J. E. Whittington;B. Keats;J. Jackson;R. Currier;P. Terasaki
谱系分析的五个家庭中，一种形式的脊髓小脑性共济失调（SCA 1）是目前已被用来获得更多的信息SCA 1的位置在染色体6上。与HLA和Glycoproteinase I（GLO）的结合率表明顺序为HLA-GLO-SCA 1。没有证据表明胃蛋白酶原同工酶5（PG）与HLA或GLO连锁。
Pedigree analyses of five families in which a form of spinocerebellar ataxia (SCA1) is present have been used to obtain additional information on the location of SCA1 on chromosome 6. Recombination rates with HLA and glyoxalase I (GLO) suggest that the order is HLA-GLO-SCA1. There was no evidence for linkage of pepsinogen isozyme-5 (PG) either to HLA or GLO.