Electrotherapy reoxygenates inframalleolar ischemic wounds on diabetic patients: a case series.
Electrotherapy reoxygenates inframalleolar ischemic wounds on diabetic patients: a case series.
复制标题
DOI：
10.1097/00129334-200205000-00006
复制
发表时间：
2002-05-01
影响因子：
2.4
通讯作者：
Golden, Michael A
中科院分区：
文献类型：
--
作者：
Goldman, Robert J;Brewley, Barbara I;Golden, Michael A
目的：回顾性评价高压脉冲电流(HVPC)对严重缺血创面(经皮血氧[TcPO(2)]<10 mm Hg)微循环的促进作用，从而促进创面愈合。设计与方法：连续3例成人糖尿病患者(男3例，女3例)非手术后发生缺血性踝关节或踝下皮肤病变，每个受试者作为自己的对照。定期测量创面面积和TcPO(2)。通过二维、飞行时间磁共振血管成像对5例患者的远端动脉硬化进行评估。结果：电疗前创缘最大平均TcPO(2)为2+/-2 mm Hg。开始电疗后，最大TcPO(2)为33+/-18 mm Hg(N=6；P
OBJECTIVE: To retrospectively evaluate the ability of high voltage pulsed current (HVPC) to increase microcirculation in critically ischemic wounds (transcutaneous oxygen [TcPO(2)] less than 10 mm Hg) and, as a result, to improve wound healing.DESIGN AND METHODS: Clinical case series with successive adult diabetic subjects (3 men and 3 women) with nonsurgical ischemic malleolar or inframalleolar skin lesions, each subject serving as his or her own control. Wound area and TcPO(2) were measured periodically. Presence of distal arteriosclerosis was assessed on 5 patients by 2-dimensional, time-of-flight magnetic resonance angiography. End point was either complete wound closure or leg amputation.RESULTS: Maximum mean TcPO(2) was 2 +/- 2 mm Hg at the wound edge before the start of electrotherapy. After electrotherapy began, maximum TcPO(2) was 33 +/- 18 mm Hg (N=6; P