Mild cognitive dysfunction: An epidemiological perspective with an emphasis on African Americans
Mild cognitive dysfunction: An epidemiological perspective with an emphasis on African Americans
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DOI：
10.1177/0891988707308804
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发表时间：
2007-12-01
影响因子：
2.6
通讯作者：
Hendrie, Hugh C.
中科院分区：
文献类型：
--
作者：
Unverzagt, Frederick W.;Gao, Sujuan;Hendrie, Hugh C.
本文首先回顾了轻度认知功能障碍的概念演变的历史，包括从克拉尔到彼得森的命名和标准。本文对轻度认知功能障碍的评估和诊断的主要因素进行了批判性分析。在设计，测量和表征方法的局限性，特别是因为它们涉及到老年非裔美国人，确定。来自印第安纳州印第安纳波利斯社区居住的非裔美国人的15年纵向研究的数据表明，全因轻度认知功能障碍的患病率为23%，其中约25%在2年内进展为痴呆，另外25%在同一时间段内恢复正常认知。回顾了导致这种纵向结果变异的因素，包括医疗健康因素的作用。本文最后对轻度认知功能障碍的流行病学研究提出了建议。（J Geriatr Psychiatry Neurol 2007;20：215-226）
This review begins with a historical accounting of the evolution of the concept of mild cognitive dysfunction, including nomenclature and criteria from Kral to Petersen. A critical analysis of the main elements relating to assessment and diagnosis of mild cognitive dysfunction is provided. Methodological limitations in design, measurement, and characterization, especially as they relate to older African Americans, are identified. Data from a 15-year longitudinal study of community-dwelling African Americans in Indianapolis, Indiana, indicate a 23% prevalence of all-cause mild cognitive dysfunction, with approximately 25% progressing to dementia in 2 years and another 25% reverting to normal cognition in the same interval. Factors contributing to this longitudinal variability in outcomes are reviewed, including the role of medical health factors. The review closes with suggestions for next steps in the epidemiological research of mild cognitive impairment. ( J Geriatr Psychiatry Neurol 2007;20:215-226)