Regulation of Lipid Metabolism by Palmitoleate and Eicosapentaenoic Acid (EPA) in Mice Fed a High-Fat Diet

Regulation of Lipid Metabolism by Palmitoleate and Eicosapentaenoic Acid (EPA) in Mice Fed a High-Fat Diet
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DOI:
10.1271/bbb.110509
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发表时间:
2011-12-01
影响因子:
1.6
通讯作者:
Kasono, Keizo
Kasono, Keizo
中科院分区:
工程技术4区
文献类型:
--
作者:
Shiba, Sachiko;Tsunoda, Nobuyo;Kasono, Keizo

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我们研究了口服棕榈油酸酯是否能改善脂质代谢紊乱,以阐明鱼油成分之一的作用。棕榈油酸酯和EPA给药显著降低了肝脏和血浆中的脂质水平。这些结果表明,棕榈油酸酯,除了EPA,在鱼油的脂质代谢的调节中发挥作用。
We investigated whether oral administration of palmitoleate ameliorates disorders of lipid metabolism to clarify the effects of one of the components of fish oil. Lipid levels in the liver and plasma were significantly decreased by palmitoleate and by EPA administration. These results suggest that palmitoleate, in addition to EPA, plays a role in the regulation of lipid metabolism by fish oil.