Metastasis Research Society-American Association For Cancer Research Joint Conference on Metastasis.

Metastasis Research Society-American Association For Cancer Research Joint Conference on Metastasis.
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DOI:
10.1158/0008-5472.can-08-3360
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发表时间:
2008-12-01
期刊:
影响因子:
11.2
通讯作者:
Mastro AM
Mastro AM
中科院分区:
医学1区
文献类型:
--
作者:
Welch DR;Cooper CR;Hurst DR;Lynch CC;Martin MD;Vaidya KS;VanSaun MN;Mastro AM

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以此类推,对转移的研究就像一群盲人研究一头大象。每个人都是根据他接触的部分来描述大象,但没有人了解整个大象,因为他/她的接触有限。同样,只有当一个人从一个专门的领域退后一步,观察这个领域的情况,或者与其他研究这个过程的其他方面的研究人员交流时,才能理解转移的复杂性。生物学只提供相关的机制认识,而分子生物学和生物化学脱离生物学是没有意义的。所有学科的知识如果不能转化为临床实践,其价值是有限的。因此,2008年8月3日至7日,近500名科学家和临床医生聚集在不列颠哥伦比亚省的温哥华,参加一个由联合主办的关于癌症转移的会议。转移领域已经到了一个重要的十字路口。会议的重点不是反思过去的进展,而是概述未来研究的方向和将新发现转化为临床实践。会议没有提出正式建议;相反,它侧重于新兴的共同主题。
By analogy, the study of metastasis is like a group of blind people studying an elephant. Each describes the pachyderm based on the part (s) he touches, but none comprehends the whole elephant because his/her exposure is limited. Likewise, the complexity of metastasis can only be appreciated when one either steps back from a specialized area and examines the landscape or communicates with other researchers studying other aspects of the process. Biology provides only correlative mechanistic insight, whereas molecular biology and biochemistry are meaningless when disconnected from the biology. Knowledge from all disciplines is of limited value if it cannot be translated into clinical practice. So, nearly 500 scientists and clinicians gathered in Vancouver, British Columbia, for a jointly sponsored conference on cancer metastasis from August 3 to 7, 2008.The metastasis field has reached an important crossroads. The conference was less focused upon reflection of past progress than outlining directions for future research and translation of new findings into clinical practice. The meeting did not generate formal recommendations; rather, it focused upon emerging common themes.