Anatomical and functional differences between the Paced Auditory Serial Addition Test and the Symbol Digit Modalities Test
Anatomical and functional differences between the Paced Auditory Serial Addition Test and the Symbol Digit Modalities Test
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DOI：
10.1080/13803395.2010.481620
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发表时间：
2011-01-01
影响因子：
2.2
通讯作者：
Avila, Cesar
中科院分区：
文献类型：
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作者：
Forn, Cristina;Belenguer, Antonio;Avila, Cesar
节奏听觉序列加法测试（PASAT）和符号数字模态测试（SDMT）通常用于检测多发性硬化症患者的认知障碍。虽然两者似乎都对缓慢的信息处理速度敏感，但一些结果表明，它们并不涉及相同的认知功能。本研究的目的是观察这些任务之间可能存在的差异，以帮助理解它们对认知评估的效用。这项研究共招募了17名参与者，并完成了每个任务的分组设计版本。任务间比较采用方差分析(ANOVA; p。05、家庭错误（FWE，已更正）。在这两项任务中，我们观察到左额叶和顶叶区域的激活；然而，PASAT比SDMT激活了更多的额叶区域。这些任务需要在大范围内有效地传递信息。此外，PASAT需要执行更多的执行职能。
The Paced Auditory Serial Addition Test (PASAT) and the Symbol Digit Modalities Test (SDMT) are generally used to detect cognitive impairments in multiple sclerosis patients. Although both seem to be sensitive to the slow information-processing speed, some results suggest that they do not involve the same cognitive functions. The aim of the present study is to observe possible differences between these tasks to help understand their utility to cognitive assessment. A total of 17 participants were recruited for the study and completed a block-design version of each task. Comparisons between tasks were calculated using an analysis of variance (ANOVA; p .05, familywise error, FWE, corrected). We observed activations in the left frontal and parietal areas during both tasks; however, the PASAT activated more frontal areas than did the SDMT. These tasks require an efficient transfer of information among large areas. Moreover, the PASAT requires more executive functions to be executed.