What's new about osmotic regulation of glycerophosphocholine.

What's new about osmotic regulation of glycerophosphocholine.
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DOI:
10.1152/physiol.00009.2009
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发表时间:
2009-08
期刊:
Physiology (Bethesda, Md.)
影响因子:
--
通讯作者:
Burg MB
Burg MB
中科院分区:
其他
文献类型:
--
作者:
Gallazzini M;Burg MB

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甘油磷酸胆碱是一种丰富的肾髓质有机渗透剂,可保护肾髓质细胞免受其通常暴露于的高间质浓度NaCl和尿素的影响。我们认为甘油磷酸胆碱的代谢,其渗透调节,以及最近发现的分子身份的酶,甘油磷酸胆碱调节其丰度。
Glycerophosphocholine is an abundant renal medullary organic osmolyte that protects renal medullary cells from the high interstitial concentrations of NaCl and urea to which they are normally exposed. We consider the metabolism of glycerophosphocholine, its osmotic regulation, and the recently discovered molecular identity of the enzymes that osmoregulate its abundance.
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