Dementia among Elderly in Shanghai Suburb: A Rural Community Survey
Dementia among Elderly in Shanghai Suburb: A Rural Community Survey
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上海郊区老年人痴呆：农村社区调查
DOI：
10.3233/jad-131601
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发表时间：
2014-01-01
影响因子：
4
通讯作者：
Jiang, Guo-Xin
中科院分区：
文献类型：
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作者：
Cheng, Qi;Sun, Hong-Xian;Jiang, Guo-Xin
世界上老年人的数量正在迅速增加，尤其是在中国。对上海西南郊区佘山镇某社区老年人痴呆患病率进行了调查。采用面对面访谈的方式，用准备好的问卷收集相关信息。使用中文版的简易精神状态测验（Mini-Mental Status Examination）筛查认知障碍（CI）受试者。进行体格检查和神经心理评估。老年痴呆及其主要亚型阿尔茨海默病（Alzheimer's disease， AD）和血管性痴呆（vascular Dementia, VaD）由资深神经科医师根据相关诊断标准进行诊断。此外，对一些AD或VaD患者进行了磁共振成像和脑电图（P300）检查。这项研究共有1472名参与者（666名男性和806名女性），年龄在60岁及以上。共筛选了167名CI患者。其中，痴呆确诊79例，患病率5.37%（95%可信区间4.22% ~ 6.52%）。诊断为AD 53例（男16例，女37例），患病率3.60%(95%可信区间2.65% ~ 4.55%)；诊断为VaD 21例（男5例，女16例），患病率1.43%(95%可信区间0.82% ~ 2.03%)；AD / VaD比值为2.52。在我们的研究中，老年痴呆症的患病率高于之前报道的中国，但与世界上大多数地区的报道一致。建议在全国范围内建立痴呆症患病率调查和监测系统。
The number of elderly in the world is increasing rapidly, especially in China. The prevalence of dementia among elderly was investigated in a community of Sheshan town, located in the Southwest suburb of Shanghai, China. Face-to-face interviews were conducted to collect relevant information with prepared questionnaires. The Chinese version of the Mini-Mental Status Examination was used to screen subjects with cognitive impairment (CI). Physical examinations and neuropsychological assessments were carried out. Dementia and its major subtypes, Alzheimer's disease (AD) and vascular dementia (VaD), were diagnosed by senior neurologists according to relevant diagnostic criteria. In addition, magnetic resonance imaging and EEG (with P300) were performed for a number of cases with AD or VaD. There were 1,472 participants (666 males and 806 females) aged 60 years and over in the study. A total of 167 subjects with CI were screened. Among them, dementia was recognized in 79 cases with a prevalence of 5.37% (95% confidence intervals: 4.22%-6.52%). The diagnosis of AD was made for 53 cases (16 males and 37 females) with a prevalence of 3.60% (95% confidence intervals: 2.65%-4.55%), and VaD for 21 cases (5 males and 16 females) with a prevalence of 1.43% (95% confidence intervals: 0.82%-2.03%); while the ratio of AD to VaD was 2.52. The prevalence rates of dementia among elderly from our study are higher than that previously reported from China, but in line with that reported from most world regions. A nationwide survey and surveillance system on the prevalence of dementia is recommended.