Comparison of saliva PCR assay versus rapid culture for detection of congenital cytomegalovirus infection.

Comparison of saliva PCR assay versus rapid culture for detection of congenital cytomegalovirus infection.
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DOI：
10.1097/inf.0000000000000609
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发表时间：
2015-05
期刊：
The Pediatric infectious disease journal
影响因子：
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通讯作者：
National Institute on Deafness and Other Communication Disorders CMV and Hearing Multicenter Screening (CHIMES) Study
National Institute on Deafness and Other Communication Disorders CMV and Hearing Multicenter Screening (CHIMES) Study
中科院分区：
其他
文献类型：
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作者：
Pinninti SG;Ross SA;Shimamura M;Novak Z;Palmer AL;Ahmed A;Tolan RW Jr;Bernstein DI;Michaels MG;Sánchez PJ;Fowler KB;Boppana SB;National Institute on Deafness and Other Communication Disorders CMV and Hearing Multicenter Screening (CHIMES) Study
来源链接：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400866/?report=classic

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作为CMV和听力多中心筛查（CHIMES）研究的一部分，72239名新生儿通过唾液样本的快速培养和实时PCR筛查CMV。266例先天性巨细胞病毒感染患儿中，14例患儿快速培养与PCR检测结果不一致，13例患儿仅PCR检测结果不一致，说明PCR检测方法的优越性。
As part of the CMV and Hearing Multicenter Screening (CHIMES) study, 72,239 newborns were screened for CMV by rapid culture and real-time PCR of saliva samples. Of the 266 infants with congenital CMV infection, discordance between rapid culture and PCR was observed in 14 children and 13 were identified only by PCR, demonstrating the superiority of the PCR assay.