Onychomycosis secondary to onychomadesis: an underdiagnosed manifestation.
Onychomycosis secondary to onychomadesis: an underdiagnosed manifestation.
复制标题
继发于甲脱症的甲真菌病：一种诊断不足的表现。
作者：
Li Meirong;Chen Zhuanggui;Yin Songchao;Xue Ruzeng;Chen Zhirui;Huang Huaiqiu;Wei Ling;Lu Chun;De Hoog Gerit Sybren;Lai Wei;Feng Peiying
甲真菌病是一种罕见的儿童早期指甲疾病，而甲发育是一种影响甲基质的周期性特发性非炎症性疾病，在儿童中很常见，特别是那些遭受病毒感染的儿童。在这项研究中，我们调查了最近的病例甲真菌病随后的时期的甲发育的儿童。16名儿童（男6名，女10名）平均年龄36.5个月，诊断为甲发育，其中13例患者在甲改变前有病毒感染史。直接镜检甲鳞阳性11例（68.8%），培养阳性11例（68.8%）。分离到4种念珠菌，其中以光秃念珠菌最多，共8例（72.7%）；白色的,C。parapsilosisandC。每一种都是在一个病例中遇到的。使用或不使用局部双苯唑治疗，所有儿童均获得成功。
Onychomycosis is a rare nail disorder in early childhood, while onychomadesis is a periodic idiopathic, non‐inflammatory disease that affects the nail matrix and is common in children especially in those who suffer from viral infections. In this study, we investigated recent cases of onychomycosis subsequent to periods of onychomadesis in children. Sixteen young children (six males, 10 females) with a mean age of 36.5 months were diagnosed with onychomadesis, and 13 of the patients had a history of viral infection prior to nail changes. Direct microscopy of nail scaling was positive in 11 cases (68.8%), and culture was positive in the same number of cases. FourCandidaspecies were isolated:Candida glabratawas the most frequent, found in eight cases (72.7%), whileC. albicans,C. parapsilosisandC. tropicalis, each were encountered in a single case. All children were treated successfully with or without topical bifonazole therapy.