Superparamagnetic iron oxide nanoparticles for bio-medical applications
Superparamagnetic iron oxide nanoparticles for bio-medical applications
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DOI：
10.1016/s1359-6462(01)00870-3
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发表时间：
2001-05-18
影响因子：
6
通讯作者：
Muhammed, M
中科院分区：
文献类型：
--
作者：
Kim, DK;Zhang, Y;Muhammed, M
结论采用化学共沉淀法制备了非离子表面活性剂聚氧乙烯（10）油醚包覆的超顺磁性Fe3O4纳米粒子，粒径分布窄，可作为MRI诊断示踪剂。MRI结果表明，这些纳米颗粒具有超顺磁性，可在MRI扫描仪中检测到，因此是MR造影剂的合适基质。此外，纳米颗粒的小尺寸使得它们可以选择性地被
ConclusionNonionic surfactant (polyoxyethylene (10) oleyl ether) coated superparamagnetic Fe 3 O 4 nanoparticles with narrow size distribution were prepared by chemical coprecipitation method as a diagnostic tracer for MRI imaging. The MRI results have indicated that these nanoparticles have a superparamagnetic property that is detectable in an MRI scanner, thus to be a suitable substrate for MR contrast agents. Furthermore, the small size of the nanoparticles makes it possible for them to be selectively