Calculation of the properties of digital mammograms using a computer simulation

Calculation of the properties of digital mammograms using a computer simulation
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DOI:
10.1093/rpd/nch519
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发表时间:
2005-01-01
影响因子:
1
通讯作者:
Carlsson, GA
Carlsson, GA
中科院分区:
环境科学与生态学4区
文献类型:
--
作者:
Hunt, RA;Dance, DR;Carlsson, GA

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蒙特卡罗乳房x线摄影计算机模型已经开发研究和优化数字乳房x线摄影系统的性能。该程序使用高分辨率体素模型来模拟乳房,以三维方式模拟脂肪和纤维腺组织、库珀韧带、导管和皮肤。该模型计算每个组织的剂量,以及传递给图像像素的能量、每个图像像素的噪声和散射与初级(SIP)比等数量。它允许研究图像属性对乳房结构和图像内位置的依赖。通过计算和测量数字x光成像系统的像素值和噪声,对程序进行了校准。该系统的两个组件的厚度未知,并进行了调整,以获得测量和计算之间的良好一致性。通过计算有网格和没有网格的SIP比的变化,以及50毫米厚乳房幻影图像的图像对比度,证明了该程序的实用性。
A Monte Carlo computer model of mammography has been developed to study and optimise the performance of digital mammographic systems. The program uses high-resolution voxel phantoms to model the breast, which simulate the adipose and fibroglandular tissues, Cooper's ligaments, ducts and skin in three dimensions. The model calculates the dose to each tissue, and also the quantities such as energy imparted to image pixels, noise per image pixel and scatter-to-primary (SIP) ratios. It allows studies of the dependence of image properties on breast structure and on position within the image. The program has been calibrated by calculating and measuring the pixel values and noise for a digital maminographic system. The thicknesses of two components of this system were unknown, and were adjusted to obtain a good agreement between measurement and calculation. The utility of the program is demonstrated with the calculations of the variation of the SIP ratio with and without a grid, and of the image contrast across the image of a 50-mm-thick breast phantom.