Ru-catalyzed asymmetric hydrogenation of racemic aldehydes via dynamic kinetic resolution: Efficient synthesis of optically active primary alcohols
Ru-catalyzed asymmetric hydrogenation of racemic aldehydes via dynamic kinetic resolution: Efficient synthesis of optically active primary alcohols
复制标题
通过动态动力学拆分Ru-催化外消旋醛的不对称氢化：光学活性伯醇的高效合成
DOI：
10.1021/ja0680109
复制
发表时间：
2007-02-21
影响因子：
15
通讯作者：
Zhou, Qi-Lin
中科院分区：
文献类型：
--
作者：
Xie, Jian-Hua;Zhou, Zhang-Tao;Zhou, Qi-Lin
以[RuCl2(sdp)（二胺）]配合物为催化剂，建立了外消旋α -芳醛的高效不对称加氢反应，得到了具有优异对映选择性的手性伯醇。
A highly efficient asymmetric hydrogenation of racemic alpha-arylaldehydes via dynamic kinetic resolution has been developed by using [RuCl2(SDPs)(diamine)] complexes as catalysts, providing chiral primary alcohols in excellent enantioselectivities.