Peripheral blood neutrophils in inflammatory bowel disease: morphological evidence of in vivo activation in active disease
Peripheral blood neutrophils in inflammatory bowel disease: morphological evidence of in vivo activation in active disease
复制标题
炎症性肠病中的外周血中性粒细胞:活动性疾病中体内激活的形态学证据
DOI:
--
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发表时间:
1991
影响因子:
4.6
通讯作者:
Y.
中科院分区:
文献类型:
--
作者:
D. McCarthy;D. Rampton;Y.
Morphological evidence of activation in vivo of circulating neutrophils in patients with inflammatory bowel disease (IBD) was sought by quantitative light microscope examination of toluidine bluestained leucocyte preparations made from peripheral venous bloods that had been fixed immediately ex vivo. The proportion of spherical (unactivated) circulating neutrophils was reduced in active Crohn's disease (73%; 46–96 (median; range), n= 11) compared with inactive Crohn's (90%; 45–99; n= 18, P<0.01) and normal subjects (94%; 44–98; n=13, P<0.05). There tended to be fewer spherical neutrophils in active ulcerative colitis (77%; 13–96; n= 17) than in quiescent colitis (88%; 57–99, n= 13, P<0.1) or normal subjects (P<0.05). Activated neutrophils occur in the circulating pool of patients with active IBD and can be detected by light microscopy of peripheral venous blood leucocyte preparations.
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影响因子:
4.4
作者:
T. Tedder;Ann C. Penta;H. Levine;A. Freedman
通讯作者:
T. Tedder;Ann C. Penta;H. Levine;A. Freedman
DOI:
--
发表时间:
1983
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Fearon,DT;Collins,LA
通讯作者:
Collins,LA
DOI:
--
发表时间:
1985-04
期刊:
The American journal of pathology
影响因子:
--
作者:
C. Haslett;L. Guthrie;Marguerite M. Kopaniak;B. Richard;Johnston;P. Henson
通讯作者:
C. Haslett;L. Guthrie;Marguerite M. Kopaniak;B. Richard;Johnston;P. Henson
影响因子:
56.9
作者:
KISHIMOTO, TK;JUTILA, MA;BUTCHER, EC
通讯作者:
BUTCHER, EC
影响因子:
4
作者:
Hoover,RL;Folger,R;Haering,WA;Ware,BR;Karnovsky,MJ
通讯作者:
Karnovsky,MJ