Moderate red wine consumption is associated with a lower prevalence of the metabolic syndrome in the PREDIMED population
Moderate red wine consumption is associated with a lower prevalence of the metabolic syndrome in the PREDIMED population
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DOI：
10.1017/s0007114514003262
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发表时间：
2015-04-01
影响因子：
3.6
通讯作者：
Estruch, Ramon
中科院分区：
文献类型：
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作者：
Tresserra-Rimbau, Anna;Medina-Remon, Alexander;Estruch, Ramon
先前关于酒精摄入与代谢综合征（MetS）发展之间关系的研究得出了不一致的结果。此外，很少有研究分析了红葡萄酒（RW）消费对代谢综合征及其组分患病率的影响。由于适度RW饮用者具有更好的血脂谱和更低的糖尿病、高血压和腹部肥胖（MetS的所有组成部分）发生率，因此假设适度RW饮用可能与MetS的患病率较低相关。在PREDIMED研究中纳入的5801例心血管高风险老年参与者的横断面研究中，3897例在基线时符合MetS标准。使用经过验证的137项FFQ记录RW摄入量。进行多元逻辑回归分析，以估计RW摄入量和MetS患病率之间的关联。与不饮酒者相比，中度RW饮酒者（>= 1杯/d）的MetS患病风险降低（OR 0.56，95%CI 0.45，0.68; P
Previous studies on the association between alcohol intake and the development of the metabolic syndrome (MetS) have yielded inconsistent results. Besides, few studies have analysed the effects of red wine (RW) consumption on the prevalence of the MetS and its components. As moderate RW drinkers have a better lipid profile and lower incidence rates of diabetes, hypertension and abdominal obesity, all components of the MetS, it was hypothesised that moderate RW consumption could be associated with a lower prevalence of the MetS. In the present cross-sectional study of 5801 elderly participants at a high cardiovascular risk included in the PREDIMED (Prevencion con Dieta Mediterranea) study, 3897 fulfilled the criteria of the MetS at baseline. RW intake was recorded using a validated 137-item FFQ. Multiple logistic regression analysis was carried out to estimate the association between RW intake and the prevalence of the MetS. Compared with non-drinkers, moderate RW drinkers (>= 1 drink/d) were found to have a reduced risk of prevalent MetS (OR 0.56, 95% CI 0.45, 0.68; P