The tert-amino effect in heterocyclic chemistry:: Synthesis of new fused pyrazolinoquinolizine and 1,4-oxazinopyrazoline derivatives
The tert-amino effect in heterocyclic chemistry:: Synthesis of new fused pyrazolinoquinolizine and 1,4-oxazinopyrazoline derivatives
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DOI：
10.1186/1860-5397-3-43
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发表时间：
2007-12-12
影响因子：
2.7
通讯作者：
Borah, Kalyan Jyoti
中科院分区：
文献类型：
--
作者：
Prajapati, Dipak;Borah, Kalyan Jyoti
The synthesis of novel fused heterocycles is based on reactions proceeding by the mechanism of the tert-amino effect, which generalizes cyclization of certain derivatives of 3-methyl-1-phenyl-2-pyrazolin-5-ones. Using this strategy a variety of fused heterocycles is obtained by the Knoevenagel condensation of 5-tert-amino-3-methyl-1-phenylpyrazolone-4-carboxal-dehyde 3 with active methylene compounds such as malononitrile and cyanoacetamide followed by cyclisation using anhydrous zinc chloride.
