Nutrition risk factors for survival in the elderly living in canadian long-term care facilities

Nutrition risk factors for survival in the elderly living in canadian long-term care facilities
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DOI:
10.1111/j.1532-5415.2004.52011.x
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发表时间:
2004-01-01
影响因子:
6.3
通讯作者:
Liu, B
Liu, B
中科院分区:
医学1区
文献类型:
--
作者:
Allard, JP;Aghdassi, E;Liu, B

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目的:确定营养参数在影响机构老年人死亡风险中的作用。设计:一项前瞻性队列研究,其中受试者在基线时测量了多个营养参数,并随访 19 个月。入组后立即开始记录死亡时间和死亡率。地点:14 个长期护理机构 (LTCF)。参与者:408 名 60 岁及以上的老年长期护理居民,在该机构居住超过 6 周。测量:在基线时,使用生物电阻抗分析测量膝盖高度、体重、中臂周长 (MAC)、皮褶厚度和去脂质量。协变量包括人口统计因素、在设施中的停留时间、功能状态和医疗诊断。 Cox比例风险回归分析用于确定死亡率的独立预测因子。结果报告为平均值+/-平均值标准误差(SEM)。结果:总体而言,死亡率为28.4%。单变量预测因素包括男性、体重指数、MAC 和三头肌皮褶。在多变量分析中,男性(风险比(HR)=1.7,95%置信区间(CI)=1.2-2.7,P=.0096)和MAC小于26厘米与死亡风险增加显着相关(HR=4.8,95% CI:2.8-8.3,P
OBJECTIVES: To determine the role of nutritional parameters in influencing the risk of mortality in institutionalized elderly.DESIGN: A prospective cohort study in which subjects had several nutritional parameters measured at baseline and were followed for 19 months. Time to death and mortality were recorded starting immediately after enrollment.SETTING: Fourteen long-term care facilities (LTCFs).PARTICIPANTS: Four hundred eight elderly long-term care residents aged 60 and older who resided in the facility for more than 6 weeks.MEASUREMENTS: At baseline, knee height, weight, mid-arm circumference (MAC), skin-fold thickness, and fat-free mass using bioelectric impedance analysis were measured. Covariates included demographic factors, length of stay in the facility, functional status, and medical diagnoses. Cox proportional hazards regression analysis was used to identify independent predictors of mortality. Results are reported as mean+/-standard error of the mean (SEM).RESULTS: Overall, mortality rate was 28.4%. Univariate predictors included male sex, body mass index, MAC, and triceps skin fold. In multivariate analysis, male sex (hazard ratio (HR)=1.7, 95% confidence interval (CI)=1.2-2.7, P=.0096) and MAC less than 26 cm were significantly associated with increased risk of mortality (HR=4.8, 95% CI: 2.8-8.3, P