Urine flavonoids and plasma carotenoids in the validation of fruit, vegetable and tea intake during pregnancy in the Norwegian Mother and Child Cohort Study (MoBa)

Urine flavonoids and plasma carotenoids in the validation of fruit, vegetable and tea intake during pregnancy in the Norwegian Mother and Child Cohort Study (MoBa)
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DOI:
10.1017/s1368980007339037
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发表时间:
2007-08-01
影响因子:
3.2
通讯作者:
Meltzer, Helle Margrete
Meltzer, Helle Margrete
中科院分区:
医学3区
文献类型:
--
作者:
Brantsaeter, Anne Lise;Haugen, Margaretha;Meltzer, Helle Margrete

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目的:验证一种新的食物频率问卷 (FFQ),用于测量参与挪威母婴队列研究 (MoBa) 的妇女报告的水果、蔬菜和茶的摄入量。设计:将 FFQ 估计的水果、蔬菜和茶的摄入量与通过 4 天称重食物日记 (FD) 测量的尿类黄酮排泄量、血浆类胡萝卜素浓度和摄入量进行比较。应用三角法使用两个独立的生物标志物计算 FFQ 有效性系数。 背景和受试者: 119 名参与 MoBa 的女性。 结果:水果摄入量的 FFQ 估计值与尿根皮素 (r = 0.33)、柑橘类水果/果汁与尿橙皮素 (r = 0.44)、煮熟的蔬菜与血浆 α-胡萝卜素 (r = 0.37) 以及茶与尿显着相关山奈酚 (r = 0.41)(所有 P < 0.01)。平均而言,按 FFQ 和生物标志物分类时,60% 的参与者属于相同或相邻的五分位数。水果 (r = 0.39)、蔬菜 (r = 0.34)、三元果汁 (r = 0.50) 和茶 (r = 0.53) 的 FFQ 和 FD 之间存在显着相关性。通过三角法计算,柑橘类水果/果汁的 FFQ 有效性系数为 0.65,熟蔬菜的 FFQ 有效性系数为 0.59。 结论:验证研究表明,MoBa FFQ 可用于估计挪威孕妇的水果、果汁、蔬菜和茶摄入量,并对分布内的个体进行排名。
Objective: To validate a new food-frequency questionnaire (FFQ) for measuring the intake of fruit, vegetables and tea reported by women participating in the Norwegian Mother and Child Cohort Study (MoBa).Design: Intake of fruits, vegetables and tea estimated by the FFQ was compared with urinary flavonoid excretion, plasma carotenoid concentration and intake measured by a 4-day weighed food diary (FD). The triangular method was applied to calculate FFQ validity coefficients using two independent biomarkers.Setting and Subjects: One hundred and nineteen women participating in MoBa.Results: The FFQ estimate of fruit intake was significantly correlated with urine phloretin (r = 0.33), citrus fruit/juice with urine hesperetin (r = 0.44), cooked vegetables with plasma alpha-carotene (r = 0.37), and tea with urine kaempferol (r = 0.41) (P < 0.01 for all). On average, 60% of the participants fell into the same or adjacent quintiles when classified by FFQ and biomarkers. Significant correlations between the FFQ and FD were found for fruit (r = 0.39), vegetables (r = 0.34), juices of triads (r = 0.50) and tea (r = 0.53). The FFQ validity coefficient was 0.65 for citrus fruit/juice and 0.59 for cooked vegetables as calculated by the triangular method.Conclusions: The validation study shows that the MoBa FFQ can be used to estimate fruit, juice, vegetable and tea intake in pregnant Norwegian women, and to rank individuals within the distribution.