The role of three-dimensional power Doppler ultrasound parameters measured on hCG day in the prediction of pregnancy during in vitro fertilization treatment
The role of three-dimensional power Doppler ultrasound parameters measured on hCG day in the prediction of pregnancy during in vitro fertilization treatment
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hCG日测量的三维能量多普勒超声参数在体外受精治疗妊娠预测中的作用
DOI：
10.1016/j.ejogrb.2016.05.016
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发表时间：
2016-08-01
影响因子：
2.6
通讯作者：
Sun, Yun
中科院分区：
文献类型：
--
作者：
Zhang, Tianjie;He, Yaqiong;Sun, Yun
目的：探讨超声在体外受精 (IVF) 和胚胎移植 (ET) 期间评估子宫内膜容受性的价值。 材料和方法：只有那些处于第一个 IVF 周期、遵循标准长促性腺激素释放激素 (GnRH) 激动剂长卵巢刺激方案、并在第 3 天移植了 2 个得分最高的胚胎的患者才纳入研究。注射人绒毛膜促性腺激素（hCG）当天进行3D超声检查，测定子宫内膜厚度、子宫内膜形态、收缩期峰值速度（PSV）、舒张末期速度（EDV）、子宫内膜螺旋动脉搏动指数（PI）和阻力指数（RI）、子宫内膜体积、血管化指数（VI）、血流指数（FI）和子宫内膜血管化血流指数（VFI）和子宫内膜下区域。对妊娠组和非妊娠组、流产组和持续妊娠组进行分析。结果：本研究共纳入435例患者，其中临床妊娠235例（58.8%），流产49例。妊娠组和非妊娠组、流产组和持续妊娠组患者的子宫内膜厚度、子宫内膜体积、子宫内膜形态、子宫PI、RI、S/D、子宫内膜和子宫内膜下VI、FL和VFI均无显着差异。在子宫内膜相对较薄组中，妊娠患者的子宫内膜厚度、子宫内膜体积、子宫内膜形态、子宫PI、RI、S/D、子宫内膜和子宫内膜下VI、FL和VFI与非妊娠患者相似。结论：hCG日测量的子宫内膜3D PDUS参数不能很好地预测IVF治疗中的妊娠，也不能很好地预测持续妊娠。 (C) 2016 Elsevier Ireland Ltd. 保留所有权利。
Objective: To investigate the value of ultrasound for the assessment of endometrial receptivity during in vitro fertilization (IVF) and embryo transfer (ET).Materials and methods: Only those patients in their first IVF cycle, followed a standard long gonadotropin releasing hormone (GnRH) agonist long ovarian stimulation regimen, and had 2 highest scoring embryos transferred on day 3 were included in the study. A 3D ultrasound examination was performed on the day of human chorionic gonadotropin (hCG) injection to determine endometrial thickness, endometrial pattern, peak systolic velocity (PSV), end diastolic velocity (EDV), pulsatility index (PI) and resistance index (RI) of endometrial spiral arteries, endometrial volume, vascularization index (VI), flow index (FI) and vasculariztion flow index (VFI) of endometrial and subendometrial region. Analyses were carried on between pregnant and non-pregnant groups, and miscarriage and ongoing pregnant groups.Results: 435 patients were included in the study, in which 235 (58.8%) got clinical pregnancy, and 49 suffered miscarriage. Patients in both pregnant group and non-pregnant group, and miscarriage and ongoing pregnant group did not show significant difference in endometrial thickness, endometrial volume, endometrial pattern, uterine PI, RI, S/D, endometrial and subendometrial VI, FL and VFI. In relative thin endometrium group, pregnant patients had similar endometrial thickness, endometrial volume, endometrial pattern, uterine pi, RI, S/D, endometrial and subendometrial VI, FL and VFI with non-pregnant patients.Conclusion: 3D PDUS parameters of endometrium measured on hCG day were not good predictors of pregnancy in IVF treatment, neither good predictors of ongoing pregnancy. (C) 2016 Elsevier Ireland Ltd. All rights reserved.