Exchange of Small Regulatory RNAs between Plants and Their Pests
Exchange of Small Regulatory RNAs between Plants and Their Pests
复制标题
植物与害虫之间的小调控RNA交换
DOI：
10.1104/pp.19.00931
复制
发表时间：
2020-01-01
期刊：
影响因子：
7.4
通讯作者：
Axtell, Michael J.
中科院分区：
文献类型：
--
作者：
Hudzik, Collin;Hou, Yingnan;Axtell, Michael J.
调节性小RNA在植物中作为抗病毒剂、基因表达的调节剂和基因组完整性的捍卫者而众所周知。过去十年的几项研究也表明，植物与其病原体和寄生虫之间交换了一些小RNA。天然存在的跨物种小RNA被宿主植物用来沉默病原体中的mRNA。这些基因沉默事件被认为对病原体有害而对宿主有益。相反，来自病原体和寄生虫的跨物种小RNA被用来沉默宿主mRNA;这些事件被认为对害虫有益。植物与入侵的真核生物交换小RNA的天然能力可以被利用来提供抗病性。本文综述了植物跨种小RNA的研究现状，并讨论了未来研究中的几个突出问题。
Regulatory small RNAs are well known as antiviral agents, regulators of gene expression, and defenders of genome integrity in plants. Several studies over the last decade have also shown that some small RNAs are exchanged between plants and their pathogens and parasites. Naturally occurring trans-species small RNAs are used by host plants to silence mRNAs in pathogens. These gene-silencing events are thought to be detrimental to the pathogen and beneficial to the host. Conversely, trans-species small RNAs from pathogens and parasites are deployed to silence host mRNAs; these events are thought to be beneficial for the pests. The natural ability of plants to exchange small RNAs with invading eukaryotic organisms can be exploited to provide disease resistance. This review gives an overview of the current state of trans-species small RNA research in plants and discusses several outstanding questions for future research.