WHY DO SOME AFRICAN CHILDREN DEVELOP SEVERE MALARIA
WHY DO SOME AFRICAN CHILDREN DEVELOP SEVERE MALARIA
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DOI：
10.1016/0169-4758(91)90096-7
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发表时间：
1991-10-01
期刊：
影响因子：
--
通讯作者：
SNOW, R
中科院分区：
文献类型：
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作者：
GREENWOOD, B;MARSH, K;SNOW, R
疟疾仍然是非洲热带许多地区儿童死亡和严重疾病的一个主要原因，但只有一小部分患疟疾的儿童，可能只有1- 2%，发展为严重疾病。 为什么只有一些儿童经历严重或致命的攻击还不清楚。 在本文中，布莱恩·格林伍德（Brian Greenwood）、凯文·马什（Kevin Marsh）和罗伯特·斯诺（Robert Snow）回顾了寄生虫和宿主的一些可能影响疟疾感染结果的特征。 需要确定可能涉及的许多因素的相对重要性，以便制定合理的战略，预防疟疾流行地区儿童死于疟疾。
Malaria is still a major cause of death and severe illness among children in many parts of tropical Africa, but only a small proportion of children, perhaps 1-2%, who become ill with malaria develop severe disease. Why only some children experience a severe or fatal attack is not understood clearly. In this article, Brian Greenwood, Kevin Marsh and Robert Snow review some of those characteristics of the parasite and the host that may influence the outcome of a malaria infection. Identification of the relative importance of the many factors likely to be involved is needed in order to develop rational strategies for the prevention of deaths from malaria among children in malaria-endemic areas.