CT Detection of Subendocardial Fat in Myocardial Infarction
CT Detection of Subendocardial Fat in Myocardial Infarction
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DOI：
10.2214/ajr.08.1608
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发表时间：
2009-02-01
影响因子：
5
通讯作者：
Choi, Byoung Wook
中科院分区：
文献类型：
--
作者：
Ahn, Sung Soo;Kim, Young-Jin;Choi, Byoung Wook
客观的。我们试图系统地分析心肌梗死（MI）患者相对于各种临床参数的脂肪堆积特征。材料和方法。我们纳入了 161 名患者（129 名男性，32 名女性；平均年龄，60.7 岁），他们曾被诊断为 MI，并在 2003 年 2 月至 2005 年 4 月期间接受过 CT 冠状动脉造影。我们分析了心肌脂肪（如果存在）的特征，并比较了有心肌脂肪的患者和无心肌脂肪的患者的临床参数。 结果。 36 名 (22.4%) 心肌梗死患者的心内膜下区域发现心肌脂肪。在所有情况下，心肌脂肪都位于心内膜下区域，通常在左前降支区域检测到（75%，n = 27）。平扫CT上心肌脂肪的平均衰减值为-29.6 HU。心肌脂肪通常与较大的梗塞年龄、较轻的冠状动脉狭窄和较少的病变血管数量相关。心肌脂肪患者在随访超声心动图上有更严重的局部室壁运动异常。两组之间的年龄、性别、ST段抬高或Q波的存在、心肌酶水平升高、射血分数和随访超声心动图舒张末期左心室尺寸以及心律失常的存在没有显着差异。结论。 22.4% 的 MI 患者中检测到心肌脂肪，并且更常与梗塞后时间较长、冠状动脉狭窄较轻、病变血管数量较少以及局部室壁运动异常较严重相关。
OBJECTIVE. We sought to systemically analyze the characteristics of fat accumulation in patients with myocardial infarction (MI) relative to various clinical parameters.MATERIALS AND METHODS. We included 161 patients (129 men, 32 women; mean age, 60.7 years) who had previously been diagnosed with MI and had undergone CT coronary angiography between February 2003 and April 2005. We analyzed the characteristics of myocardial fat, if present, and compared the clinical parameters of the patients with and those without myocardial fat.RESULTS. Myocardial fat was found in the subendocardial region in 36 (22.4%) patients with MI. In all cases, the myocardial fat was located in the subendocardial region and was typically detected in the left anterior descending artery territory (75%, n = 27). The mean attenuation value of myocardial fat was -29.6 HU on unenhanced CT. Myocardial fat was more frequently associated with a greater infarct age, milder coronary artery stenosis, and fewer number of diseased vessels. Patients with myocardial fat had more severe regional wall motion abnormalities on follow-up echocardiography. Age, sex, the presence of ST elevation or Q wave, elevated levels of cardiac enzymes, ejection fraction, and end-diastolic left ventricular dimension on follow-up echocardiography, as well as the presence of arrhythmia, were not significantly different between the two groups.CONCLUSION. Myocardial fat was detected in 22.4% of MI patients and was more frequently associated with a longer postinfarct period, milder coronary artery stenosis, fewer number of diseased vessels, and more severe regional wall motion abnormalities.