Temporal event structure and timing in schizophrenia: Preserved binding in a longer "now"
Temporal event structure and timing in schizophrenia: Preserved binding in a longer "now"
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DOI：
10.1016/j.neuropsychologia.2012.07.002
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发表时间：
2013-01-01
期刊：
影响因子：
2.6
通讯作者：
van Wassenhove, Virginie
中科院分区：
文献类型：
--
作者：
Martin, Brice;Giersch, Anne;van Wassenhove, Virginie
精神分裂症患者经历时间连续性的丧失或主观时间维度的碎片化。在这里，我们提出了一个假设，即时间意识受损是由时间事件结构的扰动造成的。，规范神经动力学。为了解决这个问题，26名患者和他们匹配的对照组参加了两项使用非同步视听语音的心理物理研究。研究人员使用并比较了两项任务：第一项是多感觉结合障碍的识别任务测试，参与者在测试中报告他们在看着说话者的脸时听到的内容；在第二个任务中，我们测试了同样的视听语音刺激的感知同时性。在这两个任务中，我们使用了McGurk融合和组合，这是经典的生态有效的多感官错觉。首先，与之前的报告相反，我们的结果表明，患者的幻觉报告率与对照组没有显著差异。第二，识别任务中患者的虚幻报告对视听言语不同步的敏感性高于对照组。第三，令人惊讶的是，患者认为视听语言同步的时间比对照组长。因此，在一个时间上观察到的时间耐受性剖面。与对照组相比，判断任务对精神分裂症患者感觉结合的预测作用较小。我们将我们的研究结果解释为精神分裂症患者的时间事件结构受损，这并不特别影响感觉绑定操作，而是明确地影响与视听语音处理相关的时间信息的获取。我们的发现是在当前的神经生理框架的背景下讨论的结合和结构的感觉事件的时间。(C) 2012 Elsevier Ltd.版权所有。
Patients with schizophrenia experience a loss of temporal continuity or subjective fragmentation along the temporal dimension. Here, we develop the hypothesis that impaired temporal awareness results from a perturbed structuring of events in time-i.e., canonical neural dynamics. To address this, 26 patients and their matched controls took part in two psychophysical studies using desynchronized audiovisual speech. Two tasks were used and compared: first, an identification task testing for multisensory binding impairments in which participants reported what they heard while looking at a speaker's face; in a second task, we tested the perceived simultaneity of the same audiovisual speech stimuli. In both tasks, we used McGurk fusion and combination that are classic ecologically valid multisensory illusions. First, and contrary to previous reports, our results show that patients do not significantly differ from controls in their rate of illusory reports. Second, the illusory reports of patients in the identification task were more sensitive to audiovisual speech desynchronies than those of controls. Third, and surprisingly, patients considered audiovisual speech to be synchronized for longer delays than controls. As such, the temporal tolerance profile observed in a temporal. judgement task was less of a predictor for sensory binding in schizophrenia than for that obtained in controls. We interpret our results as an impairment of temporal event structuring in schizophrenia which does not specifically affect sensory binding operations but rather, the explicit access to timing information associated here with audiovisual speech processing. Our findings are discussed in the context of curent neurophysiological frameworks for the binding and the structuring of sensory events in time. (C) 2012 Elsevier Ltd. All rights reserved.