Triply responsive soft matter nanoparticles based on poly[oligo(ethylene glycol) methyl ether methacrylate- block -3-phenylpropyl methacrylate] copolymers
Triply responsive soft matter nanoparticles based on poly[oligo(ethylene glycol) methyl ether methacrylate- block -3-phenylpropyl methacrylate] copolymers
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DOI：
10.1039/c6py00254d
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发表时间：
2016-04
影响因子：
4.6
通讯作者：
Yiwen Pei;K. Jarrett;M. Saunders;P. Roth;C. Buckley;A. Lowe
中科院分区：
文献类型：
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作者：
Yiwen Pei;K. Jarrett;M. Saunders;P. Roth;C. Buckley;A. Lowe
描述了基于聚[低聚乙二醇甲基醚甲基丙烯酸酯-嵌段-3-甲基丙烯酸苯丙酯]（p（OEGMA-block-PPMA））共聚物的软物质纳米颗粒在甲醇和乙醇中的刺激响应特性。使用4-氰基戊酸二硫代苯甲酸酯作为RAFT介导剂的甲硫氨酸合成促进了简单地获得纳米颗粒，所述纳米颗粒仅通过改变共聚物组成（对于pPPMA嵌段的可变n，pOEGMA macro-CTA的固定平均聚合度（n））而表现出全部范围的常见形态（球体、蠕虫和囊泡）。有趣的是，我们证明，p（OEGMAx块PPMAy）纳米粒子能够引起三种类型的响应外部施加的刺激。这些材料具有两种不同但互补的可逆热响应-一种导致有序-有序转变，即形态变化，而第二种是基于与纳米颗粒中的pOEGMA冠状链相关的上临界溶解温度（UCST）型行为的可逆有序-无序转变。最后，我们报告的第一个例子，其中特定的p（OEGMA-块-PPMA）纳米粒子被证明是敏感的，除了一个有机碱-一个响应，是伴随着秩序，蠕虫球，形态过渡。
The stimulus-responsive properties of soft matter nanoparticles based on poly[oligo(ethylene glycol) methyl ether methacrylate-block-3-phenylpropyl methacrylate] (p(OEGMA-block-PPMA)) copolymers in methanol and ethanol are described. Methanolic synthesis, with 4-cyanopentanoic acid dithiobenzoate as the RAFT mediating agent, facilitates simple access to nanoparticles exhibiting the full range of common morphologies (spheres, worms and vesicles) simply by varying the copolymer composition (fixed average degree of polymerization (n) of the pOEGMA macro-CTA for variable n of the pPPMA block). Interestingly, we demonstrate that p(OEGMAx-block-PPMAy) nanoparticles are able to elicit three types of response to externally applied stimuli. These materials possess two distinct, but complementary, reversible thermal responses – one that results in an order–order transition, i.e. a morphological change, while the second is a reversible order–disorder transition based on upper critical solution temperature (UCST)-type behaviour associated with the pOEGMA coronal chains in the nanoparticles. Finally, we report the first example where specific p(OEGMA-block-PPMA) nanoparticles are shown to be sensitive to addition of an organobase – a response that is accompanied by an order–order, worm-to-sphere, morphology transition.