O-alkyl S-3,3-dimethyl-2-oxobutyl dithiocarbonates as versatile sulfur-transfer agents in radical C(sp3)-H functionalization.
O-alkyl S-3,3-dimethyl-2-oxobutyl dithiocarbonates as versatile sulfur-transfer agents in radical C(sp3)-H functionalization.
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DOI：
10.1002/asia.200700251
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发表时间：
2007-12
期刊：
影响因子：
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通讯作者：
Akinori Sato;H. Yorimitsu;K. Oshima
中科院分区：
文献类型：
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作者：
Akinori Sato;H. Yorimitsu;K. Oshima
标题化合物在醚溶剂或环烷烃中在自由基引发剂存在下的沸腾导致自由基C（sp 3）-H官能化，通过该官能化，硫原子被引入醚溶剂中的氧化碳原子处或环烷烃中。无环和环状醚，如[18]冠-6和[D8]THF，都经历硫转移。该反应可用于从简单的起始原料合成单硫代缩醛、硫醇和硫化物。
Boiling of the title compounds in ethereal solvents or cycloalkanes in the presence of a radical initiator leads to radical C(sp3)-H functionalization, by which a sulfur atom is introduced into the ethereal solvents at the oxygenated carbon atom or into the cycloalkanes. Both acyclic and cyclic ethers, such as [18]crown-6 and [D8]THF, undergo the sulfur transfer. The reaction is useful for the synthesis of monothioacetals, thiols, and sulfides from simple starting materials.