Genetic dimension of the coevolution of virulence-resistance in Drosophila -: parasitoid wasp relationships
Genetic dimension of the coevolution of virulence-resistance in Drosophila -: parasitoid wasp relationships
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DOI：
10.1038/sj.hdy.6800182
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发表时间：
2003-01-01
期刊：
影响因子：
3.8
通讯作者：
Poiriè, M
中科院分区：
文献类型：
--
作者：
Dupas, S;Carton, Y;Poiriè, M
寄生虫毒力和宿主抗性的变化可能是共同进化过程的结果。最近的理论发展导致了共同进化的“地理镶嵌理论”，根据这一理论，在某些地方会发生相互选择（热点），而在另一些地方则会发生强烈的相互选择（冷点）。对寄主-寄生系统的研究支持了这一点，揭示了受生态相互作用强度变化所支配的拮抗选择的性状的地理变异。在一个模型系统中，对这些地理变异的遗传基础进行了更详细的分析--黑腹果蝇与其特定寄生虫Leptopilina boulardi之间的相互作用--表明，冷点和热点也是由所考虑的性状的遗传变异量驱动的。我们的方法，分离参考菌株的基础上，已被发现预测同域相互作用的结果，这将有助于确定选择力负责的共同进化。在该模型中，宿主对标准化参考菌株的抗性是田间相互作用结果的弱预测因子，占地理变异的主要参数是可用宿主物种的数量，对D.黑腹果蝇在显示出更多样化的宿主群落的地区被发现。
Variations observed in parasite virulence and host resistance may be the outcome of coevolutionary processes. Recent theoretical developments have led to a 'geographic mosaic theory' of coevolution according to which there are some localities where reciprocal selection occurs (hot spots) and others where it is strongly reduced (cold spots). Studies of host-parasitoid systems back this up, revealing a geographical variation of traits subjected to antagonistic selection governed by variations in the strength of the ecological interactions. A more detailed analysis of the genetic basis of these geographic variations in a model system - the interaction between Drosophila melanogaster and its specific parasitoid Leptopilina boulardi-suggests that cold spots and hot spots are also driven by the amount of genetic variation available for the trait considered. Our approach, based on isolating reference strains, has been found to predict the result of sympatric interactions and it will be helpful in identifying the selective forces responsible for the coevolution. In this model, host resistance to a standardised reference strain is a weak predictor of the outcome of interactions in the field, and the main parameter accounting for the geographic variations is the number of host species available, with less parasitoid virulence towards D. melanogaster being found in areas displaying a more diversified host community.