Self-reported snoring and incident cardiovascular disease events: results from the Jackson Heart Study
Self-reported snoring and incident cardiovascular disease events: results from the Jackson Heart Study
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DOI：
10.1007/s11325-018-01776-1
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发表时间：
2019-09-01
影响因子：
2.5
通讯作者：
Shah, Neomi
中科院分区：
文献类型：
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作者：
Rosen, David M.;Kundel, Vaishnavi;Shah, Neomi
目的有证据表明打鼾与心血管疾病（CVD）事件（如心肌梗死和中风）的风险增加有关。关于非裔美国人之间这种联系的数据有限。因此，我们在杰克逊心脏研究（JHS）中检查了自我报告的习惯性打鼾与心血管疾病事件之间的关系，这是一项基于人群的非裔美国人队列研究。方法收集2000-2004年基线期打鼾及心血管疾病危险因素的自报资料。对参与者进行前瞻性随访，以了解CVD事件的发展。如果参与者报告打鼾“经常”或“几乎总是”，则习惯性打鼾被定义为存在，如果报告为“有时”，“从不”或“很少”，则不存在。“CVD事件包括中风、心肌梗死、冠状动脉血运重建术或致命的CHD事件。考克斯比例风险模型评估了自我报告的习惯性打鼾和CVD事件之间的独立关联，调整了多个协变量，包括年龄、性别、高血压、体重指数、糖尿病、高胆固醇血症和吸烟状况。结果打鼾组787例，平均年龄52.1岁，无打鼾组3708例，平均年龄54.9岁。打鼾组与非打鼾组的心血管事件发生率无显著差异。打鼾组中CVD事件的完全校正风险比为1.01（95%置信区间[0.69，1.47]，p值为0.96）。结论：在这一大型非裔美国人队列中，自我报告的习惯性打鼾与CVD事件无关。未来的研究提供打鼾和睡眠呼吸暂停的客观数据，可能会提供更多的信息，打鼾，心血管疾病的关联在非洲裔美国人。
Purpose Evidence suggests that snoring is associated with increased risk for cardiovascular disease (CVD) events such as myocardial infarction and stroke. Limited data exists pertaining to this association among African Americans. We therefore examined the association between self-reported habitual snoring and incident CVD in the Jackson Heart Study (JHS), a population-based cohort study of African Americans. Methods Self-reported data on snoring and risk factors for CVD were collected at baseline (2000-2004). Participants were followed prospectively for the development of incident CVD. Habitual snoring was defined as present if the participants reported it as "often" or "almost always" or absent if reported as "sometimes," "never," or "seldom." A CVD event included stroke, myocardial infarction, coronary revascularization procedure, or fatal CHD event. Cox proportional hazards models assessed the independent association between self-reported habitual snoring and incident CVD event adjusting for multiple covariates, including age, sex, hypertension, body mass index, diabetes, hypercholesterolemia, and smoking status. Results The snorer group consisted of 787 participants (mean age 52.1 years) and the nonsnorer group consisted of 3708 participants (mean age 54.9 years). Frequency of incident CVD events in the snorer group was not significantly different from the nonsnorer group. The fully adjusted hazard ratio for a CVD event in the snorer group was 1.01 (95% confidence interval [0.69, 1.47], p value of 0.96). Conclusion In conclusion, self-reported habitual snoring was not associated with incident CVD among this large African American cohort. Future studies providing objective data on snoring and sleep apnea may provide more information on the snoring-CVD association among African Americans.