Could Sleep Apnea Be Suffocating Your Gut Microbiome?
Could Sleep Apnea Be Suffocating Your Gut Microbiome?
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睡眠呼吸暂停会抑制肠道微生物群吗？
DOI：
10.1016/j.chest.2023.04.037
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发表时间：
2023
期刊：
影响因子：
9.6
通讯作者：
Taylor,StevenL
中科院分区：
文献类型：
--
作者：
Jun,JonathanC;Taylor,StevenL
阻塞性睡眠呼吸暂停是最常见的睡眠相关呼吸障碍，其特征是上呼吸道塌陷，导致睡眠片段化、间歇性缺氧和胸压变化。OSA与一系列不同的心血管疾病（CVD）独立相关，包括高血压、中风、心力衰竭、冠状动脉疾病和心房颤动。据推测，OSA增加CVD风险的机制涉及交感神经系统激活、炎症和氧化应激。
OSA is the most common sleep-related breathing disorder, characterized by episodes of upper airway collapse resulting in sleep fragmentation, intermittent hypoxia, and changes in thoracic pressure. OSA has been independently associated with a range of different cardiovascular diseases (CVDs), including hypertension, stroke, heart failure, coronary artery disease, and atrial fibrillation. The mechanisms by which OSA increases risks of CVD are speculated to involve sympathetic nervous system activation, inflammation, and oxidative stress.