Hybridization breaks species barriers in long-term coevolution of a cyanobacterial population.
Hybridization breaks species barriers in long-term coevolution of a cyanobacterial population.
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杂交打破了蓝藻种群长期共同进化的物种障碍。
DOI：
10.1101/2023.06.06.543983
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Bhaya,Devaki
中科院分区：
文献类型：
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作者：
Birzu,Gabriel;Muralidharan,HariharaSubrahmaniam;Goudeau,Danielle;Malmstrom,RexR;Fisher,DanielS;Bhaya,Devaki
细菌物种经常经历猖獗的重组，但仍保持有凝聚力的基因组身份。生态差异可以在物种之间产生重组障碍，并在短期内维持基因组簇。但这些力量能阻止长期共同进化过程中的基因组混合吗？黄石温泉中的蓝细菌由几种不同的物种组成，它们已经共同进化了数十万年，提供了一种罕见的自然实验。通过分析300多个单细胞基因组，我们发现，尽管每个物种都形成了一个独特的基因组簇，但物种内的大部分多样性是由选择驱动的杂交的结果，这种选择混合了它们的祖先基因型。这种广泛的混合与生态屏障可以保持细菌物种凝聚力的流行观点相反，并突出了杂交作为基因组多样性来源的重要性。
Bacterial species often undergo rampant recombination yet maintain cohesive genomic identity. Ecological differences can generate recombination barriers between species and sustain genomic clusters in the short term. But can these forces prevent genomic mixing during long-term coevolution? Cyanobacteria in Yellowstone hot springs comprise several diverse species that have coevolved for hundreds of thousands of years, providing a rare natural experiment. By analyzing more than 300 single-cell genomes, we show that despite each species forming a distinct genomic cluster, much of the diversity within species is the result of hybridization driven by selection, which has mixed their ancestral genotypes. This widespread mixing is contrary to the prevailing view that ecological barriers can maintain cohesive bacterial species and highlights the importance of hybridization as a source of genomic diversity.