Placental weight and placental weight to birthweight ratio in relation to Apgar score at birth: a population study of 522 360 singleton pregnancies
Placental weight and placental weight to birthweight ratio in relation to Apgar score at birth: a population study of 522 360 singleton pregnancies
复制标题
DOI：
10.1111/aogs.12509
复制
发表时间：
2014-12-01
影响因子：
4.3
通讯作者：
Vatten, Lars J.
中科院分区：
文献类型：
--
作者：
Eskild, Anne;Haavaldsen, Camilla;Vatten, Lars J.
ObjectiveTo study whether placental weight or placental weight to birthweight ratio are associated with Apgar score in the newborn 5min after birth.DesignPopulation-based registry study.SettingThe Medical Birth Registry of Norway.PopulationAll singleton live births during the period 1999-2008, a total of 522360 births.MethodsThe placental weight to birthweight ratios were divided into quartiles within 2-week intervals of gestational age at birth, hence 25% of the pregnancies were within each group. We studied the proportion of pregnancies in the highest quartile of placental weight and placental weight to birthweight ratio according to Apgar score 5min after birth, and estimated the odds ratio for Apgar score 7 if the placental weight to birthweight ratio was in the highest quartile, and used the lowest quartile as reference.Main outcome measureApgar score in the newborn 5min after birth.ResultsIn births after pregnancy week 29, and at every 2-week gestational age interval, the mean placental weight and placental weight to birthweight ratio were higher in newborn with Apgar score 7 than in infants with Apgar >7. The crude odds ratio of Apgar score 7 was 1.65 (95% CI 1.57-1.74), comparing the highest to the lowest quartile of placental weight to birthweight ratio. Adjustments for gestational age, birthweight, infant sex, maternal age, preeclampsia, diabetes and congenital malformations did not alter the odds ratio significantly.ConclusionsPlacental weight and placental weight to birthweight ratio were higher in pregnancies with infant Apgar score 7 compared with Apgar score >7.
