THE TEMPORARY NATURE OF THE INHIBITORY ACTION OF EXCESS IODIDE ON ORGANIC IODINE SYNTHESIS IN THE NORMAL THYROID
THE TEMPORARY NATURE OF THE INHIBITORY ACTION OF EXCESS IODIDE ON ORGANIC IODINE SYNTHESIS IN THE NORMAL THYROID
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DOI：
10.1210/endo-45-5-504
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发表时间：
1949-01-01
期刊：
影响因子：
4.8
通讯作者：
MEIER, JR
中科院分区：
文献类型：
--
作者：
WOLFF, J;CHAIKOFF, IL;MEIER, JR
试验。设计用于测试过量碘化物对甲状腺中碘的有机结合的抑制持续时间。过量碘化物对正常大鼠甲状腺的抑制作用是暂时的。抑制持续约26 h。尽管持续维持高水平的血浆总I （100-200 [mu]g）。%)，重要资产的形成。26小时后恢复有机I。
Expts. designed to test the duration of inhibition, by excess iodide, of organic binding of I in the thyroid gland are descr. The inhibitory action of excess iodide on the normal rat thyroid is temporary. Inhibition lasted for about 26 hrs. Despite the continued maintenance of a high level of plasma total I (100-200 [mu]g. %), the formation of significant amts. of organic I was resumed after 26 hrs.