PRESENTATION, CLINICAL COURSE, AND OUTCOME OF CHILDHOOD STROKE
PRESENTATION, CLINICAL COURSE, AND OUTCOME OF CHILDHOOD STROKE
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DOI：
10.1016/0887-8994(91)90062-p
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发表时间：
1991-09-01
影响因子：
3.8
通讯作者：
ARAM, DM
中科院分区：
文献类型：
--
作者：
LANSKA, MJ;LANSKA, DJ;ARAM, DM
我们回顾了 42 名单侧半球卒中儿童的表现、临床过程和结果。在出生后几天内发现中风的婴儿通常会出现癫痫发作。这些婴儿在新生儿时几乎没有异常的神经系统发现，但随着粗大运动的发展，偏瘫变得明显。出生后第一年发现中风的婴儿通常表现为病理性早期手部偏爱，没有发作史。在随后的发育过程中，这些儿童的运动缺陷变得更加明显，导致神经系统异常明显进展。在年龄较大的儿童中发现的中风通常表现为突然的偏瘫，通常与癫痫发作有关。这些儿童的偏瘫在发病时最严重，随后所有患者的力量都有所改善。功能结果是可变的。在最后一次随访中，所有儿童均可行走，其中一些儿童出现临床上明显的偏瘫。 42 名儿童中有 8 名 (19%) 出现复发性癫痫发作，发作时间从中风后 4 个月到 10 多年（中位时间：26 个月）不等。
We reviewed the presentations, clinical courses, and outcomes of 42 children with unilateral hemispheric stroke. Infants with strokes identified within the first few days of life usually presented with seizures. These infants had few abnormal neurologic findings as neonates, but hemiparesis became evident as gross motor development proceeded. Infants with strokes identified later in the first year of life usually presented with pathologic early hand preference without a history of an ictus. During subsequent development, the motor deficits in these children became more evident, producing an apparent progression of the neurologic abnormalities. Strokes identified in older children typically presented as sudden hemiparesis, often associated with seizures. The hemiparesis in these children was most severe at the onset, followed by some improvement in strength in all patients. Functional outcome was variable. At last follow-up, all children were ambulatory, some with clinically apparent hemiparesis. Eight of the 42 children (19%) developed recurrent seizures with an onset ranging from 4 months to more than 10 years (median: 26 months) after the stroke.