Desorption of small ionic fragments from oligonucleotides induced by low energy carbon ions
Desorption of small ionic fragments from oligonucleotides induced by low energy carbon ions
复制标题
低能碳离子诱导寡核苷酸中小离子片段的解吸
DOI:
10.1140/epjd/e2010-00083-x
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发表时间:
2010
期刊:
影响因子:
--
通讯作者:
Ptasinska S
中科院分区:
文献类型:
--
作者:
Ptasinska S
The degradation of oligonucleotide films containing differing base sequences induced by 4 keV C+ions has been studied experimentally. The oligonucleotides were deposited onto a gold coated stainless steel substrate and the anions and cations released from the films were analyzed by a quadrupole mass spectrometer. The total ion desorption yield was recorded as a function of time using a constant C+ion flux of 6 × 1014ions cm-2s-1. At low fluences the formation of small ionic fragments was observed, whilst for fluences greater than 1.2 × 1018ions cm-2molecules were sputtered from the substrate. In addition to studies of the influence of a particular base to the total cation desorption yield, the effect of base substitution with bromine was measured for negative ion desorption. These results showed a strong degradation of oligonucleotide films during ion bombardment.
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