Three-year follow-up of the impact of Kumamoto Earthquake on acute myocardial infarctions: An interrupted time series analysis

Three-year follow-up of the impact of Kumamoto Earthquake on acute myocardial infarctions: An interrupted time series analysis
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熊本地震对急性心肌梗死影响的三年随访:间断时间序列分析

DOI:
10.1016/j.ahjo.2022.100246
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发表时间:
2023
期刊:
American Heart Journal Plus: Cardiology Research and Practice
影响因子:
--
通讯作者:
Tsujita Kenichi
Tsujita Kenichi
中科院分区:
--
文献类型:
--
作者:
Kojima Sunao;Michikawa Takehiro;Tsujita Kenichi

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研究目的本研究旨在调查熊本地震后三年内急性心肌梗死(AMI)的发病率和后续结果是否与地震前的潜在趋势不同。来自熊本县的一家机构参与,能够接收AMI患者并进行冠状动脉造影和介入治疗。结果地震后AMI发病率与地震前相比,其RR为1.12(95%可信区间[CI]:1.00 - 1.25),与地震前相比,地震后AMI发病率与地震前相比,其RR为1.12(95%可信区间[CI]:1.00-1.25),与地震前相比,其RR为1.12(95%可信区间[CI]:1.00-1.25)。糖尿病患者(RR:1.20,95%CI:1.01-1.44)、吸烟者(RR:1.27,95%CI:1.03-1.56)和体重指数>25 kg/m2者(RR:1.27,95%CI:1.06-1.52)的AMI发生率增加。发病至入院时间>12小时的AMI患者数量增加(RR:1.46,95% CI:1.02-2.08),入院时Killip分级较高(RR:1.37,95% CI:1.13-1.67),未进行紧急冠状动脉造影(RR:1.40,95%CI:1.02-1.91),可能影响后续院内心脏事件结论熊本地震对急性心肌梗死发病率的增加和随后的住院心脏结局有影响。应确保紧急医疗服务,以便像往常一样管理高危患者,特别是在地震后立即进行管理。
Study objectiveThis study aimed to investigate whether the incidence of acute myocardial infarction (AMI) and subsequent outcomes over the three years after the Kumamoto earthquake differed from the underlying trend before the earthquake.DesignQuasi-experimental design.SettingTwenty-one institutions participating from the Kumamoto Prefecture and capable of receiving AMI patients and performing coronary angiography and interventions.ParticipantsIn total 6553 consecutive patients with AMI between 2013 and 2019 were included in this study.InterventionsInterrupted time series analysis.Main outcome measure(s)AMI incidence and following cardiac events after the earthquake.ResultsThe rate ratio (RR) for AMI incidence after the earthquake was 1.12 (95 % confidence interval [CI]: 1.00–1.25) with reference to that before the earthquake. AMI rates increased among people with diabetes mellitus (RR: 1.20, 95 % CI: 1.01–1.44), those with current smoking (RR: 1.27, 95 % CI: 1.03–1.56), and those with a body mass index >25 kg/m2(RR: 1.27, 95 % CI: 1.06–1.52). Increased number of AMI patients with onset-to-door time >12 h (RR: 1.46, 95 % CI: 1.02–2.08), a high Killip class on hospital admission (RR: 1.37, 95 % CI: 1.13–1.67), and unperformed emergent coronary angiography (RR: 1.40, 95 % CI: 1.02–1.91) were frequently observed after the earthquake, which may affect following in-hospital cardiac events (RR: 1.49, 95 % CI: 1.03–2.15).ConclusionsThe Kumamoto earthquake had an impact on the increase in the incidence of AMI and the following in-hospital cardiac outcomes. Emergency medical care should be ensured in such a way that high-risk patients are managed as usual, especially immediately after earthquake.
DOI: --
发表时间: 2014
影响因子: 3.3
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K. Hao;J. Takahashi;K. Ito;S. Miyata;Y. Sakata;T. Nihei;R. Tsuburaya;T. Shiroto;Yoshitaka Ito;Y. Matsumoto;M. Nakayama;S. Yasuda;H. Shimokawa
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DOI: 10.1016/s0002-8703(97)80023-3
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影响因子: 4.8
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