Depression comorbid with anxiety: Results from the WHO study on Psychological Disorders in Primary Health Care
Depression comorbid with anxiety: Results from the WHO study on Psychological Disorders in Primary Health Care
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DOI：
10.1192/s0007125000298395
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发表时间：
1996-06-01
影响因子：
10.5
通讯作者：
Wittchen, HU
中科院分区：
文献类型：
--
作者：
Sartorius, N;Ustun, TB;Wittchen, HU
世界卫生组织关于“一般卫生保健中的心理问题”的合作研究调查了 15 个国际地点初级保健机构中常见心理问题的形式、频率、过程和结果。该研究采用了两阶段的病例发现程序。 25916 名咨询医疗保健服务的成年人接受了 GHQ-12 治疗。第二阶段评估（n=5438）包括综合国际诊断访谈（CIDI）、社会残疾量表和问卷。对可能的精神障碍病例或边缘病例以及已知病例的样本进行了三个月和一年的随访。使用标准诊断算法 (ICD-10)，计算当前疾病（一月）和终生经历疾病的患病率。在所有接受调查的一般医疗机构中，明确的心理问题都很常见（中位数为 24.0%）。其中最常见的是抑郁、焦虑、酗酒、躯体形式障碍和神经衰弱。百分之九的患者患有阈下病症，“不符合诊断标准，但具有临床上显着的症状和功能障碍”。最常见的同时出现的是抑郁和焦虑。合并症增加了在一般医疗保健中识别精神障碍的可能性以及接受治疗的可能性。
The World Health Organization collaborative study on ''Psychological Problems in General Health Care'' investigated the form, frequency, course and outcome of common psychological problems in primary care settings at 15 international sites. The research employed a two-stage case-finding procedure. GHQ-12 was administered to 25916 adults who consulted health-care services. The second-stage assessment (n=5438) consisted of the Composite International Diagnostic Interview (CIDI) the Social Disability Schedule, and questionnaires. Possible cases or borderline cases of mental disorder, and a sample of known cases, were followed up at three months and one year. Using standard diagnostic algorithms (ICD-10), prevalence rates were calculated for current disorder (one,month) and lifetime experience disorder. Well-defined psychological problems are frequent in all the general health-care settings examined (median 24.0%). Among the most common were depression, anxiety, alcohol misuse, somatoform disorders, and neurasthenia. Nine pet cent of patients suffered from a(n) subthreshold condition ''that did not meet diagnostic criteria but had clinically significant symptoms and functional impairment. The most common co-occurrence was depression and anxiety. Comorbidity increases the likelihood of recognition of mental disorders in general health care, and the likelihood of receiving treatment.