Cognitive Deficits in Chronic Fatigue Syndrome and Their Relationship to Psychological Status, Symptomatology, and Everyday Functioning
Cognitive Deficits in Chronic Fatigue Syndrome and Their Relationship to Psychological Status, Symptomatology, and Everyday Functioning
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DOI：
10.1037/a0032084
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发表时间：
2013-03-01
期刊：
影响因子：
2.4
通讯作者：
Mathias, Jane L.
中科院分区：
文献类型：
--
作者：
Cockshell, Susan J.;Mathias, Jane L.
目的：研究慢性疲劳综合征（CFS）患者的认知缺陷及其与心理状态、CFS症状和日常功能的关系。方法：目前的研究比较了（反应时间、注意力、记忆力、运动功能、言语能力和视觉空间能力）与健康对照组（n = 50）的比较，所有这些人都表现出高水平的努力和良好表现的意图，并检查心理状态、CFS症状、和日常功能与认知表现有关。结果如下：CFS组显示受损的信息处理速度（反应时间），相对于对照组，但在注意力，记忆力，运动功能，语言能力和视觉空间能力测试中的表现相当。此外，信息处理速度与精神状态、抑郁、焦虑、CFS症状的数量或严重程度、疲劳、睡眠质量或日常功能无关。结论：信息处理速度减慢似乎是CFS患者的主要认知缺陷，其努力测试的表现不受影响。重要的是，这种减缓似乎不是其他CFS相关变量的结果，如抑郁和疲劳，或运动速度。
Objective: To examine cognitive deficits in people with chronic fatigue syndrome (CFS) and their relationship to psychological status, CFS symptoms, and everyday functioning. Method: The current study compared the cognitive performance (reaction time, attention, memory, motor functioning, verbal abilities, and visuospatial abilities) of a sample with CFS (n = 50) with that of a sample of healthy controls (n = 50), all of whom had demonstrated high levels of effort and an intention to perform well, and examined the extent to which psychological status, CFS symptoms, and everyday functioning were related to cognitive performance. Results: The CFS group showed impaired information processing speed (reaction time), relative to the controls, but comparable performance on tests of attention, memory, motor functioning, verbal ability, and visuospatial ability. Moreover, information processing speed was not related to psychiatric status, depression, anxiety, the number or severity of CFS symptoms, fatigue, sleep quality, or everyday functioning. Conclusion: A slowing in information processing speed appears to be the main cognitive deficit seen in persons with CFS whose performance on effort tests is not compromised. Importantly, this slowing does not appear to be the consequence of other CFS-related variables, such as depression and fatigue, or motor speed.